SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a390f7be880d0d7045d369080503e33a6486e656a591d637b13ca14a2c10869' 
  AND token = '73MUHTz6r8NMVJEZvUK/r1k2Sn/b/AEDFYVRhFYw6oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}