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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9645a9881ffc7cec136a22b345fc0cf6b7d456d76efad3c4a9abf1ce75603088' 
  AND token = 'Ceg4+FNLWyp57EV6S3oigja2FSBDYbdBIiVrPMA3XTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}