SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd685dcbcdb60bf808bde453820bbd27cdb80bd1a0c0d49dcc205bbdc36406b24' 
  AND token = 'fXdNnh0aq+YyhQI8MYntHLxaKwq1n6z4El6LgZcCanQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}