SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c20d0c9e2700bc7f2840fa095ee2425ab470306e8ac1250eda583f7bc8027c' 
  AND token = 'va0c86agyuo2qytNyEd9YUNfLFD4a9VZ2H+1EhhENgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}