SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6878b2a3ca25a9b80edae41b7d4c2ce3a4e13a34c8886400e34107a131dea111' 
  AND token = 'MPOQvKfFTS66mwriXOBnM2CvGU3ipdrjxjaeqTiZ6GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}