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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81a078e2743003f07589e1f7c9d9c831fd8bd660c9961fc0f8b31ade6dd31f9' 
  AND token = 'TT6sf8CClcypzmy5jLY2BjGIt5lEuaUVlaAOcp5Ri0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}