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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b12d91000e33daad422954f09dde3b2217a077a148b1a9338c3bc92245eed3' 
  AND token = '7YPtmmGPrS+Nx/1hld1akO5ytcsp6pzArXdA+8+kxYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}