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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec68119aad85202f8f16c04324bda4608aff977569f2df3ede7bca7c19a2186' 
  AND token = 'MZLbhkzHqSMN/zens43UTWgrJsZBA0W3OnEwCALU0/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}