SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c485017304cec5c234ae780b3f5655ca277b51a4cbf2c0c14907f256f44718da' 
  AND token = 'zw6bCfOD3h/J3uoMv6E/d8IPAG8sFFsxV+vx5JY4lSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}