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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '515bab8e94ba89475a629855db15897faa26e99ab0bd7b21c7c1637d620c218a' 
  AND token = 'VX/1igzT/X9tbVRlJQyEVu581ZBNDXFeGXBDLzSZ8lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}