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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21129ea3ba1553a698f3ed164e04323b6d349bb5f2aa2da957ed812653e41a89' 
  AND token = '/P3dIi/N7L9M7bjSHlnLWSMd/Ge4RPJPjsGbLEj+F+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}