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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8875a2337350491ef1b048849a628e9c416b893acbb9ec94c70b309c92c16962' 
  AND token = 'tdTGLZkWKFLHN7byPO+a7JCtQmxv0k/79rOv2hN/u6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}