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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66acdf306d753862b47e6e04119dabcb76eb1dc5a6ee50a2eba83e195fb7bed2' 
  AND token = 'YTX6EjGUleHvP3/o++GSpK6Y+kQW3+Xq5Ifkm3Nr4qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}