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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3205de4b1f08df2cd1ea7dd3072597d4ac7380e5f439cc91365036fd6d8b02ac' 
  AND token = 'RQOr4YyaSkF5CbOT70XpxUTr5iTcC51e9QiCLvXMC/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}