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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f83a44b3e4f9cb8109295e533e3be38dee1d509be74b8872ef15445e80b4b42' 
  AND token = 'q+fOVzaNRWDQ4JTU/X6k2oO0nm1jka5D0nHmQvpw5f0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}