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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18e32fdfffac95cb17898e0b8c44955e18fe1c3e8b788961c30fbb448bfc68e' 
  AND token = 'gXsk/PhGX9+2UUYrmWzqJ5UgarbWxiOus026fOdjPo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}