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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c60fa4602e318a69df271f2c7c62f2726dfef133c2ac902c25b3f8c5233c9c' 
  AND token = 'ArxsdbnLhpQ+ycsfDmodTMe/Xy/bkoUJ/xmzHmE1XM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}