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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1507d66ea0d1e91c325c642e8e0f31f047dae9c1a1dd08ff3a6c095c7491a6' 
  AND token = 'tV9IMUvoAMTgKB2LMXHFamXgS0Ho5mna5j4DDSPWHxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}