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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c544b701242664650f03ba5bd4343bbde48ad727b031ba5ff82708f202c99ed' 
  AND token = 'aS+3XDhKddzF578o/5AfMCVl2CiqyaT/N2ytFPG0OrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}