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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eb1e241e76f634430bd8f62c6d44df2311b1bc5ab6ab0b517aac4be00bea711' 
  AND token = '53KUL1vcOqVA1Q/lAZzNNB6qMXVFRu4nPA/MVtFgoBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}