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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5fb28051938ccd42a52183c22b58d9d36c0db0191d5be52d028d9901105d577' 
  AND token = 'a1nAcwwr+24RBDIknjm/VRTac6PMlCbW0rd6Kalnj00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}