SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e132e299168d34f25ba221568251e386bf351484ccee09f1f2bec1f8a42bf86' 
  AND token = 'nfSTk4r6cLYWS+idhJ1xZyk9EZnmyIfeYUVD4B6/oJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}