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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc2c1ccd2ac42314c75bcd447cfc054953664f31bb14e53ca308229e63b7722' 
  AND token = 'K9+t4KwPJdLwxaE24rTJo9dHB9V/b6AsTK8m+cC48Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}