SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57865d1d41f526cd136aef245a60663114d7b64ced2cf81d1036e0383511170c' 
  AND token = '+vWS3XO1Wt3Oxlck8HWz7e2ejjSpyJz9Z+0MxGFPbSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}