SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657adb55dda890a9d2e8c345bfa7bf00e2cba517f2dc66e32fbfa66d1cebc9e9' 
  AND token = 'LWpnD6aR6GXZob3sJQrqjixGYWvYf0IZJLKP9oDeLlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}