SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e849e78544a9c6154cafd8db16e997b0f5ec5d220955e8b57bd89dbba0d0dd1b' 
  AND token = 'qWBd4gt97RV02Gxiri2asN9HSARWqv3GuIw0AIeiw7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}