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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f858ea58c7bad0af0857ab146ffd972b9bc731c2f4b411f5e12d6954153d2f0' 
  AND token = 'AMi1Dv2EIAiNzMjuLCMrc199Iri1j0VJ0L+ZAcR09nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}