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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b88dc4f995af4b42d2d62050e0f779cc4ed8cedb0bfd28e59501bf994c8061' 
  AND token = 'VoXZlqkvT8n1PSAP9X9V0E+9waPv2HFN8gva4AIvMlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}