SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9c43aa73000e480eb5fe5534d5e2bd24a1514c30cff3e6e9c9de0feb0f51c5f' 
  AND token = 'jQZRm7n86jc507uwpVk9SsD3Mmid6ucuSjkoYeMXEq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}