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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3a22f12ba728fc7f846f0c037950830576b52c6dc79b53e21d69ae57dc365f' 
  AND token = '/tiawo6CiAg6wpeaWRSQN1p9Y+AQdEdu7iyUQMEJJZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}