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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e88de3e3f1360a2b9527a304946200f27bf8f30ed2c5955a4b4c93a0148ee771' 
  AND token = 'RWUIhHvhmpR7SB3SxU+rFhYEZbmIijXpkLcDe58LlO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}