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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afcb6a32d2c0d32f9e2b3471aca37b0f574ea4ce837c662508615f12c3441184' 
  AND token = 'bbACsRpzRDul7lMaehLpgh7NKrzVW53lnyDKD/ov0DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}