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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f18a9699c1238ca125bbee6ea1c254575be0d327613292a4c52b735a2a1adbb' 
  AND token = '9zQB2re1XxvxpQqKomyMyGJ2n7NIGPFdkN37Y9ZaeRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}