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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a2534fb213d4cccddb19aa77add57c6596dad65bb4b2e0859c0909dfbc0a46' 
  AND token = 'NyzxDyrbFybxouJWQWKA9vlkE477ivYqsKw1X15RUdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}