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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8381f1d304305c7ed8fbf6a7c6a50749a60128a39d428d49650fdc21a45be1c' 
  AND token = 'fp72fxB1Qyacz2XQL1DRE7kY32XSc+Z2sYQYMHt9N28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}