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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad8bfe190ec18ed111a39ca387280bb2fc047237960b1f82fce06fbcf25d6ef' 
  AND token = 'VeTh24h055CcqutTHv6KS2pD2Q5q9ir9aVzU2uaE4/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}