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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7164ab0cdd7d2396edcabed9c73d08b0574e2151d8761826c48ef7b358b31eb8' 
  AND token = 'USIIBQzndf5d+goFsHD1HyuXe0ziBQJrzvfhgImuQ/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}