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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c1a3975c22e3248ba77d8ffe2b48eaea4c2705bd5d1728195239c8677421a4' 
  AND token = 'nN6c29UcG0iiZXYr9+1/hz5lRSQbeKfkfbfEVQgdz7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}