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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a50887bb4ee7039d8e53e2b797fcb09c800f64056b2b66b7dc835ef8688adb0' 
  AND token = 'To+t2mlxxmEDaEfsquhXOl/EQnBQGwX+pg2U7p7HUtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}