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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f2d5a118940b00ebea0305eaf6bb84d2906dde085b2b88f8327f284133a198' 
  AND token = 'OiPc04wSkHEGsAfFAiQE/sAeoOE9WckqhjdIwROxOSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}