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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d296e9c0aa541aa5bc44d481a4c10e7941924b1283e3e2a60f288da6e2dbcab' 
  AND token = 'wpUHwQORv4rFvKrBukiicqs/DjJU780a8iqEXuIyMG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}