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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec25c2c920169f8fb5a1111d24bcd4c877d08f849369d7714fb9a4bbbcb09e5' 
  AND token = 'gCY1l2wpwz3cO6JH2MdldGAp0o/I//78CHOMWtIYtUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}