SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3776a61b4a4c9da4269c780cac6b22a34a37f47b78a5ec9a0875898e727c646' 
  AND token = '1xJfrqDV6vFXTk4WAgzNki7igEYSyqQHX5ArgWRa3nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}