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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3f339e4346bf8ce5378e63cace9bedde33f94accba2b76e434c0565a826ed7' 
  AND token = 'Hc2x68IQ6apnx8ZGff2qT2zuupSTBGaZ7IYFEM/t2tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}