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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e3e5888e44abfb54b4225d99e8226014b1611923e816df35b7ae21944545a6' 
  AND token = 'hvpCAt08WA3bPFvN87K/IN13ALJ3MN6NEwUcEj3fKKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}