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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101f5b7da485ce4fe8ba188a56c5adfcd67b2798d42492d7e2964cce66dccc6a' 
  AND token = 'Y+uejvAHnahu/oSH/Qvf+oXcAPATsH1FH/wkoFG4oh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}