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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888a1d0bb738fba92bc07071c9b1f8270ccf7b9b2610521f13a9f8bb9ba54845' 
  AND token = 'qjml9BoEDszQY1SJdYxcnhytpyzp1raJsTWixq8WZ4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}