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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d42b7544a3ed9895e47a1f8ebac784a0d4d90b200bb69ec2e693c21e32cc677' 
  AND token = 'TS1qpbwAcp8xpAZxPHxWGsn23tTGUdLy+q4gCniF9Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}