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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a5e8daf4f1e66aebd1052e02c6b17ba3ed85f0d03ef5a447c041f3f49066b9c' 
  AND token = 'kyz9uz300DsHhi4ktF4sZYb8bxdGdv+lpqJO61cEHH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}