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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7778e2b6b72af3aea3b4ef8e1e1b09a4f7a3a5c9be64f9eff5746dad487a711c' 
  AND token = 'toCw0Cwqcr8EAELazIB4gjNhAoww/lZmVSoGxl0cF80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}